Pharmaceutical Glass Ampoules

Pharmaceutical Glass Ampoules for Injectables & Biologicals

Pharmaceutical glass ampoules are sealed glass containers made from a single tube of neutral borosilicate glass, filled and then flame-sealed at the neck to create a completely hermetic primary package. Because there is no elastomer closure in contact with the product — only glass — ampoules offer the lowest possible interaction risk for sensitive injectable formulations, which is why they remain the reference container for anaesthetics, emergency drugs, vaccines and biological products.

Rimzer supplies ampoules in Type I neutral borosilicate glass from 1mL to 20mL, with either a straight-stem or funnel-form opening and a colour-break ring at the neck for controlled, sterile opening. The glass meets the hydrolytic resistance requirements of USP, EP and CP pharmacopoeias, and each production lot is inspected for dimensional accuracy, wall thickness, internal stress and cosmetic defects before packing. Ampoules are supplied clean and ready for filling, and can be matched with the corresponding aluminium-plastic crimp caps from the same factory so that container and closure are qualified together.

Quick facts: MOQ 100,000 pcs  |  Lead time 10–18 days  |  Free samples  |  Custom volumes, colour-break ring, printing and shrink-wrap available

Specifications

Applications

Supplied to pharmaceutical manufacturers, hospital compounding units and contract fillers across South America, Southeast Asia, the Middle East and Europe. Typical uses include:

• Anaesthetics and emergency drugs — 2–10mL ampoules where rapid, sterile opening matters.
• Vitamins and injectable supplements — small-volume parenterals in clear or amber glass.
• Vaccines and biologicals — single-dose ampoules where glass-only contact is preferred.
• Diluents and irrigation solutions — 10–20mL saline and electrolyte ampoules.
• Diagnostic reagents — small volumes requiring an inert, low-extractable container.

Key Advantages

• Glass-only product contact — no elastomer or plastic in contact with the formulation, minimising extractables and leachables.
• Fully hermetic flame seal — the sealed tip isolates the contents from air, moisture and microorganisms for the whole shelf life.
• Type I borosilicate — high hydrolytic resistance and near-zero alkali release, suitable for pH-sensitive formulations.
• Colour-break ring — scores the neck so the ampoule opens cleanly in one direction, reducing glass-particle risk.
• Light protection option — amber glass for photosensitive drugs.
• Matched with Rimzer caps — container and closure sourced together, so fitment and validation are handled as one package.

Why Choose Taizhou Rimzer

Taizhou Rimzer Rubber & Plastic Co., Ltd has over 20 years of experience in pharmaceutical and bottle packaging, with a 23,000 m² facility and 85 skilled staff serving 100+ customers in more than 30 countries. We supply containers, seal liners and closures from one source — from glass ampoules and their aluminium-plastic caps to induction seal liners and vented closures — so you qualify and reorder everything with a single supplier. Every ampoule lot ships with dimensional inspection records, and pharmacopoeia compliance documents are available on request.

Frequently Asked Questions

Which glass type should I choose — Type I or Type II?

Type I neutral borosilicate is the default for injectables because it has the highest hydrolytic resistance and releases almost no alkali. Type II is soda-lime glass with an inner surface treatment; it is adequate for many non-pH-sensitive products and is more economical. Tell us the formulation pH and the pharmacopoeia you file under, and we will advise.

Can you supply the caps together with the ampoules?

Yes — that is one of our advantages. We make the aluminium-plastic caps in 13mm to 22mm, so container and closure come from the same factory and are dimensionally matched.

Are the ampoules clean and ready for filling?

They are supplied clean and packed to avoid particulate contamination. If your line needs washed and depyrogenated ampoules, tell us — we can quote that process as an option.

How do you prevent glass particles when the ampoule is opened?

The colour-break ring is a controlled score line at the neck. When the top is snapped in the direction of the dot, the break follows the score, keeping fragments in the top section rather than the body. We also supply opening instructions for your clinical leaflet.

Do you offer amber glass for light-sensitive drugs?

Yes, amber glass is a standard option for photosensitive formulations. Transmission curves are available on request.

What documentation comes with each lot?

Dimensional inspection records and visual defect inspection results. Pharmacopoeia compliance statements (USP, EP, CP) and hydrolytic resistance test reports are available for your regulatory file on request.

What is the MOQ and lead time?

MOQ is 100,000 pcs. Lead time is 10–18 days after order confirmation, depending on volume and whether the size is a stock mould or a new tool.

Are samples free?

Yes. Sample quantity and courier cost are negotiable based on your location and project.